Incresng+EUS+Sensitivity+and+Specificity

Pancreatic Cancer – Improving sensitivity and specificity

“Pancreatic Cancer – EUS and early diagnosis” Brief Abstract EUS is known to be the best possible solution to screening pancreatic cancer. With higher powered EUS doctors were able to both increase sensitivity and specificity. However NPV of EUS is still high, indicating that PPV is very low.

Improvement in EUS - 86 patients examined - 73.2% sensitivity and 83.3% specificity (original) - 91.1% sensitivity and 93.3% specificity (contrast-enhanced power mode) - Difference is via observation of perfusion (pumping of fluid) of microvessels - NPV for locoregional extension (44%), lymph node involvement (65%), vascular invasion (74%)

“ Role of Repeated Endoscopic Ultrasound-Guided  Fine Needle Aspiration in Small Solid Pancreatic  <span style="color: #231f20; font-family: 'Georgia','serif'; font-size: 12pt; mso-bidi-font-family: MyriadPro-Bold; mso-bidi-font-weight: bold; mso-fareast-font-family: MyriadPro-Bold;">Masses with Previous Indeterminate and Negative <span style="color: #231f20; font-family: 'Georgia','serif'; font-size: 12pt; mso-bidi-font-family: MyriadPro-Bold; mso-bidi-font-weight: bold; mso-fareast-font-family: MyriadPro-Bold; mso-fareast-language: KO;"> <span style="color: #231f20; font-family: 'Georgia','serif'; font-size: 12pt; mso-bidi-font-family: MyriadPro-Bold; mso-bidi-font-weight: bold; mso-fareast-font-family: MyriadPro-Bold;">Cytological Findings <span style="color: #231f20; font-family: 'Georgia','serif'; font-size: 12pt; mso-bidi-font-family: MyriadPro-Bold; mso-bidi-font-weight: bold; mso-fareast-font-family: MyriadPro-Bold; mso-fareast-language: KO;">”

Brief Abstract EUS-FNA is a suggestible method of screening for pancreatic cancer. Research shows that repetition of EUS-FNA improves sensitivity and specificity.

Results from the article <span style="font-family: 'Georgia','serif'; font-size: 12pt; mso-bidi-font-family: Georgia; mso-fareast-font-family: Georgia; mso-fareast-language: KO; msobidifontfamily: Georgia; msofareastfontfamily: Georgia; msofareastlanguage: KO; msolist: Ignore;">- <span style="font-family: 'Georgia','serif'; font-size: 12pt; mso-bidi-font-family: 바탕; mso-fareast-font-family: 바탕; mso-fareast-language: KO;">Screening was done 3 times <span style="font-family: 'Georgia','serif'; font-size: 12pt; mso-bidi-font-family: Georgia; mso-fareast-font-family: Georgia; mso-fareast-language: KO; msobidifontfamily: Georgia; msofareastfontfamily: Georgia; msofareastlanguage: KO; msolist: Ignore;">- <span style="font-family: 'Georgia','serif'; font-size: 12pt; mso-bidi-font-family: 바탕; mso-fareast-font-family: 바탕; mso-fareast-language: KO;">Malignant (17), benign (24), intermedicate (9); out of 47 pancreatic lesions scanned via EUS-FNA <span style="font-family: 'Georgia','serif'; font-size: 12pt; mso-bidi-font-family: Georgia; mso-fareast-font-family: Georgia; mso-fareast-language: KO; msobidifontfamily: Georgia; msofareastfontfamily: Georgia; msofareastlanguage: KO; msolist: Ignore;">- <span style="font-family: 'Georgia','serif'; font-size: 12pt; mso-bidi-font-family: 바탕; mso-fareast-font-family: 바탕; mso-fareast-language: KO;">Out of 22 benign 21 TP and 1 FN (with EUS-FNA done 3 times